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MSD Biotech Dublin Retrofit | Jacobs Engineering : Fit Out or Refurbishment Over €10m

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Project: MSD Biotech Dublin Retrofit
Client: MSD Biotech Dublin
Design Team: Jacobs Engineering

MSD Ireland is at the forefront of science and technology to advance manufacturing excellence and R & D across their Irish sites and global company network. Approximately half of MSD’s top twenty products are manufactured in Ireland, helping save and enhance lives in over sixty countries around the world.

In 2018 construction began on MSD Biotech, in Swords, Co. Dublin and has progressed at an impressive rate since then.  The site plays a pivotal role in the manufacture of MSD’s biologics-based medicines, including immuno-oncology, and has expanded MSD’s current internal network of biologics drug substance manufacturing plants since full manufacturing operations began in 2021. ​

This particular project entailed significant retrofit and upgrades to equipment and facilities within the MSD Biotech facility in Swords. The project purpose was to increase the production capacity and sustainability for the client’s life enhancing cancer therapy.

Jacobs’ scope included engineering, procurement, construction management and commissioning of the works within a constrained operational shutdown window, without impacting production.

Despite some initial uncertainty as to whether the project would be completed according to schedule, it was successfully completed thanks to meticulous planning and best-in-class field execution.

The project team earned this nomination based on:

  • Exceptional pre-planning,
  • Risk management and OSM application to achieve the target schedule in a GMP operating environment without impacting operations.
  • Project delivered 5% below final approved budget.
  • Zero incident rate from >350,000 site hours in a COVID restriction environment.
  • ‘Right first-time’ delivery with an overall average of <1 defect per system.